Result Interpretation Framework & Common Interferences¶
A POCT result is not a diagnosis — it is data to be interpreted in clinical context. This page provides an interpretation framework and the common interferences that can skew results.
The Interpretation Framework¶
- Is the result valid? — QC passed, sample acceptable.
- Above or below cutoff? — the qualitative answer.
- How far from cutoff? — borderline values warrant caution.
- What is the trend? — serial results beat single values.
- Does it fit the clinical picture? — correlate with signs.
The Trend Principle¶
A single value is a snapshot; a trend is a story. CRP falling from 85 → 20 mg/L tells you treatment is working — a single "positive" does not.
Common Interferences¶
| Interference | Affected analytes | Mitigation |
|---|---|---|
| Hemolysis | Various | Recollect; note in record |
| Lipemia | Various | Fast; note in record |
| Recent vaccination | CPV/FPV/CDV antigen | Correlate with clinical signs |
| Maternal antibody | FIV/CDV antibody (young) | Retest after 6 months |
| Renal disease | NT-proBNP | Interpret with renal function |
Borderline Results¶
A value just at the cutoff is a signal to recheck, not a diagnosis. Recheck in 24–48 hours or correlate with additional testing.
FAQ¶
What if the result contradicts the clinical picture? Trust the clinical picture and investigate — recollect, check for interference, or pursue confirmatory testing.
How important is the trend? For monitoring (CRP, progesterone, SDMA), the trend is more informative than any single value.
For panels, see Diagnostic Panels.
Authored by: Migibio Clinical & Scientific Affairs, Guangzhou Magic Biotech Co., Ltd.
Reviewed by: Migibio R&D Quality Committee
Last updated: 2026-08-13
Disclosure: Migibio (Guangzhou Magic Biotech Co., Ltd.) is the manufacturer of the FIA680/FIA880 analyzers and FICT reagents referenced in this content. See our Editorial & Review Policy.